Contact:
YCR P53 Research Unit
Department of Biology
University of York
YORK YO10 5DD, UK.
Tel (within UK):
(01904) 328620
Fax: (01904) 328622
Tel (outside UK):
+44-1904-328620
Fax: +44-1904-328622
E-mail: ajm24@york.ac.uk
Jo Milner, PhD
Director, Yorkshire Cancer Research P53 Research Unit
Professor of Cell Biology, Department of Biology, University of York, UK
Professor Jo Milner is Director of the YCR P53 Research Unit and Professor of Cell Biology in the Department of Biology at the University of York. Whilst at York Professor Milner has raised £8m research funding. Professor Milner has served on numerous international and national advisory boards and committees, including the Scientific Advisory Board of Aura Biosciences developing next generation nano drug therapy. She continues to promote scientific research both at the academic and public level. She has also organised international workshops integrating basic science with clinical development and with business development.
Professor Milner was awarded a State Scholarship to study for her B.Sc., obtained her PhD from the University of Cambridge and was a post-doctoral Research Fellow at Harvard Medical School, Boston (USA) before being awarded a Beit Memorial Fellowship for Medical Research. This she held at the University of Cambridge (UK) where she was also awarded a college Fellowship at New Hall. She continued her research at the University of Cambridge for some 20 years before moving to York in 1991.
Jo Milner’s work has focused on cellular growth control genes and cancer. She showed that p53 is a normal cellular protein which can exist naturally in different conformations depending on cell growth state. She also discovered mutant phenotypic dominance driven by wild type/mutant protein/protein interactions. This evidence was used to support Prusiner’s prion hypothesis for the conversion of wild-type PrP into PrPSc. More recently she has been employing RNAi to analyse basal versus stress-induced regulation of apoptosis in cancer and non-cancer cells.
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